Using the Statistical Machine Learning Models ARIMA and SARIMA to Measure the Impact of Covid-19 on Official Provincial Sales of Cigarettes in Spain

From a public health perspective, tobacco use is addictive by nature and triggers several cancers, cardiovascular and respiratory diseases, reproductive disorders, and many other adverse health effects leading to many deaths. In this context, the need to eradicate tobacco-related health problems and the increasingly complex environments of tobacco research require sophisticated analytical methods to handle large amounts of data and perform highly specialized tasks. In this study, time series models are used: autoregressive integrated moving average (ARIMA) and seasonal autoregressive integrated moving average (SARIMA) to forecast the impact of COVID-19 on sales of cigarette in Spanish provinces. To find the optimal solution, initial combinations of model parameters automatically selected the ARIMA model, followed by finding the optimized model parameters based on the best fit between the predictions and the test data. The analytical tools Autocorrelation Function (ACF), Partial Autocorrelation Function (PACF), Akaike Information Criterion (AIC), and Bayesian Information Criterion (BIC) were used to assess the reliability of the models. The evaluation metrics that are used as criteria to select the best model are: mean absolute error (MAE), root mean square error (RMSE), mean absolute percentage error (MAPE), mean percentage error (MPE), mean error (ME) and mean absolute standardized error (MASE). The results show that the national average impact is slight. However, in border provinces with France or with a high influx of tourists, a strong impact of COVID-19 on tobacco sales has been observed. In addition, the least impact has been observed in border provinces with Gibraltar. Policymakers need to make the right decisions about the tobacco price differentials that are observed between neighboring European countries when there is constant and abundant cross-border human transit. To keep smoking under control, all countries must make harmonized decisions. © 2023, Universidad Internacional de la Rioja. All rights reserved.

Leveraging probe data to model speeding on urban limited access highway segments: Examining the impact of operational performance, roadway characteristics, and COVID-19 pandemic.

Stay-at-home orders - imposed to prevent the spread of COVID-19 - drastically changed the way highways operate. Despite lower traffic volumes during these times, the rate of fatal and serious injury crashes increased significantly across the United States due to increased speeding on roads with less traffic congestion and lower levels of speed enforcement. This paper uses a mixed effect binomial regression model to investigate the impact of stay-at-home orders on odds of speeding on urban limited access highway segments in Maine and Connecticut. This paper also establishes a link between traffic density and the odds of speeding. For this purpose, hourly speed and volume probe data were collected on limited access highway segments for the U.S. states of Maine and Connecticut to estimate the traffic density. The traffic density was then combined with the roadway geometric characteristics, speed limit, as well as dummy variables denoting the time of the week, time of the day, COVID-19 phases (before, during and after stay-at-home order), and the interactions between them. Density, represented in the model as Level of Service, was found to be associated with the odds of speeding, with better levels of service such as A, or B (low density) resulting in the higher odds that drivers would speed. We also found that narrower shoulder width could result in lower odds of speeding. Furthermore, we found that during the stay-at-home order, the odds of speeding by more than 10, 15, and 20 mph increased respectively by 54%, 71% and 85% in Connecticut, and by 15%, 36%, and 65% in Maine during evening peak hours. Additionally, one year after the onset of the pandemic, during evening peak hours, the odds of speeding greater than 10, 15, and 20 mph were still 35%, 29%, and 19% greater in Connecticut and 35% 35% and 20% greater in Maine compared to before pandemic.

New ways of interacting with data, context, and chance in statistical modeling processes

This introductory paper first summarizes the major accomplishments of the literature on data modeling, modeling with software and the integration of statistical and computational thinking in statistical modeling, including how these collective efforts have helped the field evolve. Next, challenges that the field must address and general suggestions for future research are discussed. Finally, it is important to note that the papers in this special issue were in their final editing stages in early to mid-2020, at which time there were an unprecedented confluence of global crises: Covid-19, Civil Unrest over Racism, and Climate Change. Although the papers were written prior to Covid-19, it would be remiss not to discuss some of the important themes cultivated in this special issue in light of current events, particularly around the relationship between the non-neutral nature of data and ideas of data, context and chance in statistical modeling. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

Real-time estimation and forecasting of COVID-19 cases and hospitalizations in Wisconsin HERC regions for public health decision making processes.

BACKGROUND: The spread of the COVID-19 (SARS-CoV-2) and the surging number of cases across the United States have resulted in full hospitals and exhausted health care workers. Limited availability and questionable reliability of the data make outbreak prediction and resource planning difficult. Any estimates or forecasts are subject to high uncertainty and low accuracy to measure such components. The aim of this study is to apply, automate, and assess a Bayesian time series model for the real-time estimation and forecasting of COVID-19 cases and number of hospitalizations in Wisconsin healthcare emergency readiness coalition (HERC) regions. METHODS: This study makes use of the publicly available Wisconsin COVID-19 historical data by county. Cases and effective time-varying reproduction number [Formula: see text] by the HERC region over time are estimated using Bayesian latent variable models. Hospitalizations are estimated by the HERC region over time using a Bayesian regression model. Cases, effective Rt, and hospitalizations are forecasted over a 1-day, 3-day, and 7-day time horizon using the last 28 days of data, and the 20%, 50%, and 90% Bayesian credible intervals of the forecasts are calculated. The frequentist coverage probability is compared to the Bayesian credible level to evaluate performance. RESULTS: For cases and effective [Formula: see text], all three time horizons outperform the three credible levels of the forecast. For hospitalizations, all three time horizons outperform the 20% and 50% credible intervals of the forecast. On the contrary, the 1-day and 3-day periods underperform the 90% credible intervals. Questions about uncertainty quantification should be re-calculated using the frequentist coverage probability of the Bayesian credible interval based on observed data for all three metrics. CONCLUSIONS: We present an approach to automate the real-time estimation and forecasting of cases and hospitalizations and corresponding uncertainty using publicly available data. The models were able to infer short-term trends consistent with reported values at the HERC region level. Additionally, the models were able to accurately forecast and estimate the uncertainty of the measurements. This study can help identify the most affected regions and major outbreaks in the near future. The workflow can be adapted to other geographic regions, states, and even countries where decision-making processes are supported in real-time by the proposed modeling system.

A new Cosine-Weibull model: Distributional properties with applications to basketball and medical sectors

The two-parameter classical Weibull distribution is commonly implemented to cater for the product's reliability, model the failure rates, analyze lifetime phenomena, etc. In this work, we study a novel version of the Weibull model for analyzing real-life events in the sports and medical sectors. The newly derived version of the Weibull model, namely, a new cosine-Weibull (NC -Weibull) distribution. The importance of this research is that it suggests a novel version of the Wei-bull model without adding any additional parameters. Different distributional properties of the NC-Weibull distribution are obtained. The maximum likelihood approach is implemented to esti-mate the parameters of the NC-Weibull distribution. Finally, three applications are analyzed to prove the superiority of the NC-Weibull distribution over some other existing probability models considered in this study. The first and second applications, respectively, show the mortality rates of COVID-19 patients in Italy and Canada. Whereas, the third data set represents the injury rates of the basketball players collected during the 2008-2009 and 2018-2019 national basketball associ-ation seasons. Based on four selection criteria, it is observed that the NC-Weibull distribution may be a more suitable model for considering the sports and healthcare data sets.(c) 2022 THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/ 4.0/).

Estimation of the serial interval of monkeypox during the early outbreak in 2022.

With increased transmissibility and novel transmission mode, monkeypox poses new threats to public health globally in the background of the ongoing COVID-19 pandemic. Estimates of the serial interval, a key epidemiological parameter of infectious disease transmission, could provide insights into the virus transmission risks. As of October 2022, little was known about the serial interval of monkeypox due to the lack of contact tracing data. In this study, public-available contact tracing data of global monkeypox cases were collected and 21 infector-infectee transmission pairs were identified. We proposed a statistical method applied to real-world observations to estimate the serial interval of the monkeypox. We estimated a mean serial interval of 5.6 days with the right truncation and sampling bias adjusted and calculated the reproduction number of 1.33 for the early monkeypox outbreaks at a global scale. Our findings provided a preliminary understanding of the transmission potentials of the current situation of monkeypox outbreaks. We highlighted the need for continuous surveillance of monkeypox for transmission risk assessment.

Influence of COVID-19 vaccination on the dynamics of new infected cases in the world.

The initial COVID-19 vaccinations were created and distributed to the general population in 2020 thanks to emergency authorization and conditional approval. Consequently, numerous countries followed the process that is currently a global campaign. Taking into account the fact that people are being vaccinated, there are concerns about the effectiveness of that medical solution. Actually, this study is the first one focusing on how the number of vaccinated people might influence the spread of the pandemic in the world. From the Global Change Data Lab "Our World in Data", we were able to get data sets about the number of new cases and vaccinated people. This study is a longitudinal one from 14/12/2020 to 21/03/2021. In addition, we computed Generalized log-Linear Model on count time series (Negative Binomial distribution due to over dispersion in data) and implemented validation tests to confirm the robustness of our results. The findings revealed that when the number of vaccinated people increases by one new vaccination on a given day, the number of new cases decreases significantly two days after by one. The influence is not notable on the same day of vaccination. Authorities should increase the vaccination campaign to control well the pandemic. That solution has effectively started to reduce the spread of COVID-19 in the world.

Predictive modeling of the COVID-19 data using a new version of the flexible Weibull model and machine leaning techniques.

Statistical modeling and forecasting of time-to-events data are crucial in every applied sector. For the modeling and forecasting of such data sets, several statistical methods have been introduced and implemented. This paper has two aims, i.e., (i) statistical modeling and (ii) forecasting. For modeling time-to-events data, we introduce a new statistical model by combining the flexible Weibull model with the Z-family approach. The new model is called the Z flexible Weibull extension (Z-FWE) model, where the characterizations of the Z-FWE model are obtained. The maximum likelihood estimators of the Z-FWE distribution are obtained. The evaluation of the estimators of the Z-FWE model is assessed in a simulation study. The Z-FWE distribution is applied to analyze the mortality rate of COVID-19 patients. Finally, for forecasting the COVID-19 data set, we use machine learning (ML) techniques i.e., artificial neural network (ANN) and group method of data handling (GMDH) with the autoregressive integrated moving average model (ARIMA). Based on our findings, it is observed that ML techniques are more robust in terms of forecasting than the ARIMA model.

An evaluation of the impact of COVID-19 lockdowns on electricity demand

The COVID-19 pandemic has given rise to significant changes in electricity demand around the world. Although these changes differ from region to region, countries that have implemented stringent lockdown measures to curtail the spread of the virus have experienced the greatest alterations in demand. Within Australia, the state of Victoria has been subject to the largest number of days in hard lockdown during the COVID-19 pandemic. We conduct an exploratory data analysis to identify predictors of demand, and have built a time series forecasting model to predict the half-hourly electrical demand in Victoria. Our model distinguishes between lockdown periods and non-restrictive periods, and aims to identify a variety of patterns that we show to be influential on electricity demand. The model thereby provides a nuanced prediction of electrical demand that captures the shifting demand profile of intermittent lockdowns.

On the implementation of a new version of the Weibull distribution and machine learning approach to model the COVID-19 data.

Statistical methodologies have broader applications in almost every sector of life including education, hydrology, reliability, management, and healthcare sciences. Among these sectors, statistical modeling and predicting data in the healthcare sector is very crucial. In this paper, we introduce a new method, namely, a new extended exponential family to update the distributional flexibility of the existing models. Based on this approach, a new version of the Weibull model, namely, a new extended exponential Weibull model is introduced. The applicability of the new extended exponential Weibull model is shown by considering two data sets taken from the health sciences. The first data set represents the mortality rate of the patients infected by the coronavirus disease 2019 (COVID-19) in Mexico. Whereas, the second set represents the mortality rate of COVID-19 patients in Holland. Utilizing the same data sets, we carry out forecasting using three machine learning (ML) methods including support vector regression (SVR), random forest (RF), and neural network autoregression (NNAR). To assess their forecasting performances, two statistical accuracy measures, namely, root mean square error (RMSE) and mean absolute error (MAE) are considered. Based on our findings, it is observed that the RF algorithm is very effective in predicting the death rate of the COVID-19 data in Mexico. Whereas, for the second data, the SVR performs better as compared to the other methods.

New ways of interacting with data, context, and chance in statistical modeling processes

This introductory paper first summarizes the major accomplishments of the literature on data modeling, modeling with software and the integration of statistical and computational thinking in statistical modeling, including how these collective efforts have helped the field evolve. Next, challenges that the field must address and general suggestions for future research are discussed. Finally, it is important to note that the papers in this special issue were in their final editing stages in early to mid-2020, at which time there were an unprecedented confluence of global crises: Covid-19, Civil Unrest over Racism, and Climate Change. Although the papers were written prior to Covid-19, it would be remiss not to discuss some of the important themes cultivated in this special issue in light of current events, particularly around the relationship between the non-neutral nature of data and ideas of data, context and chance in statistical modeling. (PsycInfo Database Record (c) 2022 APA, all rights reserved)

A new Cosine-Weibull model: Distributional properties with applications to basketball and medical sectors

The two-parameter classical Weibull distribution is commonly implemented to cater for the product’s reliability, model the failure rates, analyze lifetime phenomena, etc. In this work, we study a novel version of the Weibull model for analyzing real-life events in the sports and medical sectors. The newly derived version of the Weibull model, namely, a new cosine-Weibull (NC-Weibull) distribution. The importance of this research is that it suggests a novel version of the Weibull model without adding any additional parameters. Different distributional properties of the NC-Weibull distribution are obtained. The maximum likelihood approach is implemented to estimate the parameters of the NC-Weibull distribution. Finally, three applications are analyzed to prove the superiority of the NC-Weibull distribution over some other existing probability models considered in this study. The first and second applications, respectively, show the mortality rates of COVID-19 patients in Italy and Canada. Whereas, the third data set represents the injury rates of the basketball players collected during the 2008–2009 and 2018–2019 national basketball association seasons. Based on four selection criteria, it is observed that the NC-Weibull distribution may be a more suitable model for considering the sports and healthcare data sets.

On computational analysis of nonlinear regression models addressing heteroscedasticity and autocorrelation issues: An application to COVID-19 data.

This paper develops a method for nonlinear regression models estimation that is robust to heteroscedasticity and autocorrelation of errors. Using nonlinear least squares estimation, four popular growth models (Exponential, Gompertz, Verhulst, and Weibull) were computed. Some assumptions on the errors of these models (independence, normality, and homoscedasticity) being violated, the estimates are improved by modeling the residuals using the ETS method. For an application purpose, this approach has been used to predict the daily cumulative number of novel coronavirus (COVID-19) cases in Africa for the study period, from March 13, 2020, to June 26, 2021. The comparison of the proposed model to the competitors was done using statistical metrics such as MAPE, MAE, RMSE, AIC, BIC, and AICc. The findings revealed that the modified Gompertz model is the most accurate in forecasting the total number of COVID-19 cases in Africa. Moreover, the developed approach will be useful for researchers and policymakers for predicting purpose and for better decision making in different fields of its applications.

Influence of COVID-19-Related Restrictions on the Prevalence of Overweight and Obese Czech Children.

Apart from influencing the health of the worldwide population, the COVID-19 pandemic changed the day-to-day life of all, including children. A sedentary lifestyle along with the transformation of eating and sleep habits took place in the child population. These changes created a highly obesogenic environment. Our aim was to evaluate the current weight in the child population and identify the real effects of the pandemic. Height and weight data were collected by pediatricians from the pre-COVID-19 and post-COVID-19 periods from 3517 children (1759 boys and 1758 girls) aged 4.71 to 17.33 years. We found a significant rise in the z-score BMI between pediatric visits in the years 2019 and 2021 in both sexes aged 7, 9, 11, and 13 years. Especially alarming were the percentages of (severely) obese boys at the ages of 9 and 11 years, which exceed even the percentages of overweight boys. With the use of statistical modeling, we registered the most dramatic increment at around 12 years of age in both sexes. Based on our research in the Czech Republic, we can confirm the predictions that were given at the beginning of the pandemic that COVID-19-related restrictions worsened the already present problem of obesity and excess weight in children.

Modeling Inventory Cost Savings and Supply Chain Success Factors: A Hybrid Robust Compromise Multi-Criteria Approach

Determining success factors for managing supply chains is a relevant aspect for companies. Then, modeling the relationship between inventory cost savings and supply chain success factors is a route for stating such a determination. This is particularly important in pharmacies and food nutrition services (FNS), where the advances made on this topic are still scarce. In this article, we propose and formulate a robust compromise (RoCo) multi-criteria model based on non-linear programming and time-dependent demand. The novelty of our proposal is in defining a score that allows us to measure the mentioned success factors in a simple way, in meeting together all three elements (RoCo multi-criteria, non-linear programming, and time-dependent demand) to state a new model, and in applying it to pharmacies and FNS. This model relates inventory cost savings for pharmacy/FNS and success factors across their supply chains. Savings of inventory costs are predicted by lot sizes to be purchased and computed by comparing optimal and true inventory costs. We utilize a system that records the movements and costs of products to collect the data. Factors, such as purchasing organization, economies of scale, and synchronized supply, are assumed using the purchase system, with these factors ranked on a Likert scale. We consider multilevel relationships between savings obtained for 79 pharmacy/FNS products, and success factor scores according to these products. To deal with the endogeneity bias of the relationships proposed, internal instrumental variables are employed by utilizing generalized statistical moments. Among our main conclusions, we state that the greatest cost savings obtained from inventory models are directly associated with low-success supply chain factors. In this association, the success factors operate as endogenous variables, with respect to inventory cost savings, given the simultaneity of their relationship with cost savings when inventory decision-making.

A Statistical Model of COVID-19 Infection Incidence in the Southern Indian State of Tamil Nadu.

In this manuscript, we present an analysis of COVID-19 infection incidence in the Indian state of Tamil Nadu. We used seroprevalence survey data along with COVID-19 fatality reports from a six-month period (1 June 2020 to 30 November 2020) to estimate age- and sex-specific COVID-19 infection fatality rates (IFR) for Tamil Nadu. We used these IFRs to estimate new infections occurring daily using the daily COVID-19 fatality reports published by the Government of Tamil Nadu. We found that these infection incidence estimates for the second COVID wave in Tamil Nadu were broadly consistent with the infection estimates from seroprevalence surveys. Further, we propose a composite statistical model that pairs a k-nearest neighbours model with a power-law characterisation for "out-of-range" extrapolation to estimate the COVID-19 infection incidence based on observed cases and test positivity ratio. We found that this model matched closely with the IFR-based infection incidence estimates for the first two COVID-19 waves for both Tamil Nadu as well as the neighbouring state of Karnataka. Finally, we used this statistical model to estimate the infection incidence during the recent "Omicron wave" in Tamil Nadu and Karnataka.

Modeling the impact of the COVID-19 pandemic on speeding at rural roadway facilities in Maine using short-term speed and traffic count data.

The COVID-19 pandemic caused a significant change in traffic operations and safety. For instance, various U.S. states reported an increase in the rate of fatal and severe injury crashes over this duration. In April and May of 2020, comprehensive stay-at-home orders were issued across the country, including in Maine. These orders resulted in drastic reductions in traffic volume. Additionally, there is anecdotal evidence that speed enforcement had been reduced during pandemic. Drivers responded to these changes by increasing their speed. More importantly, data show that speeding continues to occur, even one year after the onset of the pandemic. This study develops statistical models to quantify the impact of the pandemic on speeding in Maine. We developed models for three rural facility types (i.e., major collectors, minor arterials, and principal arterials) using a mixed effect Binomial regression model and short duration speed and traffic count data collected at continuous count stations in Maine. Our results show that the odds of speeding by more than 15 mph increased by 34% for rural major collectors, 32% for rural minor arterials, and 51% for rural principal arterials (non-Interstates) during the stay-at-home order in April and May of 2020 compared to the same months in 2019. In addition, the odds of speeding by more than 15 mph, in April and May of 2021, one year after the order, were still 27% higher on rural major collectors and 17% higher on rural principal arterials compared to the same months in 2019.

Statistical Modeling for Quality Risk Assessment of Clinical Trials: Follow-Up at the Era of Remote Auditing.

BACKGROUND: As investigator site audits have largely been conducted remotely during the COVID-19 pandemic, remote quality monitoring has gained some momentum. To further facilitate the conduct of remote quality assurance (QA) activities for clinical trials, we developed new quality indicators, building on a previously published statistical modeling methodology. METHODS: We modeled the risk of having an audit or inspection finding using historical audits and inspections data from 2011 to 2019. We used logistic regression to model finding risk for 4 clinical impact factor (CIF) categories: Safety Reporting, Data Integrity, Consent and Protecting Endpoints. RESULTS: We could identify 15 interpretable factors influencing audit finding risk of 4 out of 5 CIF categories. They can be used to realistically predict differences in risk between 25 and 43% for different sites which suffice to rank sites by audit and inspection finding risk. CONCLUSION: Continuous surveillance of the identified risk factors and resulting risk estimates could be used to complement remote QA strategies for clinical trials and help to manage audit targets and audit focus also in post-pandemic times.

New SARIMA Approach Model to Forecast COVID-19 Propagation: Case of Morocco

The aim of this paper is to avoid any future health crises by analysing COVID-19 data of Morocco using Time Series to get more information about how the pandemic is spreading. For this reason, we used a statistical model called Seasonal Autoregressive Integrated Moving Average (SARIMA) to forecast the new confirmed cases, new deaths, cumulative cases and deaths. Besides predicting the spreading of COVID-19, this study will also help decision makers to better take the right decisions at the right time. Finally, we evaluated the performance of our model by measuring metrics such as Mean Squared Error (MSE). We have applied our SARIMA model for a forward forecasting in a period of 50 days, the MSE reported was 62196.46 for cumulative cases forecasting, and 621.14 for cumulative deaths forecasting.

The current COVID-19 pandemic in China: An overview and corona data analysis

At the end of December 2019, the Wuhan Municipal Health Commission, revealed several cases of pneumonia of unknown etiology. Later, this etiology was called the coronavirus disease 2019 (COVID-19). COVID-19 disease is rapidly spreading around the globe, affected millions of people, compelling governments to take serious actions. Due to this deadly disease, a number of deaths have been occurred and still increasing exponentially. In the practice and application of big data sciences, it is always of interest to provide the best description of the data. In this present article, the event background, symptoms, and preventions from COVID-19 are discussed. The steps were taken by the Chinese government to control the COVID-19 has also been discussed. Up to date, details, and data of daily discovered cases, total discovered cases, daily deaths, and total deaths around the world are presented. Moreover, a new statistical distribution is introduced to provide the best characterization of the survival times of the patients affected by the COVID-19 in China. By analyzing the survival times of the COVID-19 patient's data, it is showed that the new model provides a closer fit to COVID-19 events. (c) 2021 THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).